Question 357 · LDEK · Children with systemic diseases and disabilities

A 4-year-old child with very good oral hygiene, spontaneous gingival bleeding, petechiae and bleeding to the buccal mucosa and palate. The child complains of maxillary bone pain and painful maxillary molars, which showed no clinical or radiographic abnormalities. The symptoms suggest the need for a diagnostic evaluation for:

  1. A. diabetes mellitus.
  2. B. leukaemia.
  3. C. Langerhans cell histiocytosis.
  4. D. adrenal insufficiency.
  5. E. graft-versus-host disease.
Hint

Spontaneous bleeding despite excellent hygiene plus unexplained bone and tooth pain suggests thrombocytopenia and marrow infiltration.

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