KROK 1 Stomatology 2016 – Question 105 · KROK (Dentistry)
A 50-year-old patient has been referred for treatment of neck lymphadenitis. His individual penicillin sensitivity was tested. In 30 seconds full-body fever raised in the patient and his arterial blood pressure dropped to 0 mm Hg followed by cardiac arrest. Resuscitation was unsuccessful. Autopsy revealed acute venous hyperemia of viscera. Histological study revealed mast cells (tissue basocytes) degranulation in the skin (at the area of injections), myocardium and lungs. What kind of hypersensitivity reaction occurred in the patient?
- A. Delayed-type hypersensitivity
- B. Complement-mediated cytotoxic
- C. Immune complex-mediated
- D. Anaphylactic
- E. -
Hint
Focus on the seconds-long onset after drug exposure and the mast cell degranulation found in several organs.
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