KROK 1 Stomatology 2016 – Question 99 · KROK (Dentistry)
Osteolathyrism is characterized by a decrease in collagen strength caused by significantly less intensive formation of cross-links in collagen fibrils. This phenomenon is caused by the low activity of the following enzyme:
- A. Lysyl oxidase
- B. Lysyl hydroxylase
- C. Collagenase
- D. Prolyl hydroxylase
- E. Monoamine oxidase
Hint
Think about the step in collagen maturation that converts lysine side chains into reactive aldehydes outside the cell, and which toxin from sweet peas blocks it.
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