KROK 1 Stomatology 2016 – Question 77 · KROK (Dentistry)

On the 4th day of treatment with diclofenac sodium a 55-year-old patient has developed gastric hemorrhage due to an ulcer appearing on the gastric mucosa. Ulcerogenic action of this drug is caused by decreased secretion of:

  1. A. Thromboxane
  2. B. Prostaglandin E2
  3. C. Cyclic endoperoxides
  4. D. Leukotriene
  5. E. Prostaglandin E1
Hint

Consider which cyclooxygenase product protects the gastric mucosa by stimulating mucus and bicarbonate and reducing acid secretion.

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