KROK 1 Stomatology 2016 – Question 48 · KROK (Dentistry)

A 17-year-old girl has attempted to commit suicide by overdosing on phenobarbital. Upon arrival at the site an emergency doctor urgently performed gastric lavage on the patient and introduced bemegride and solution of sodium hydrocarbonate intravenously. The doctor introduced sodium hydrocarbonate to:

  1. A. Stimulate respiration
  2. B. Wake up the patient
  3. C. Increase renal excretion of phenobarbital
  4. D. Inactivate phenobarbital
  5. E. Normalise blood pressure
Hint

Phenobarbital is a weak acid — think about how changing urine pH affects its ionization and tubular reabsorption.

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