KROK 1 Stomatology 2015 – Question 164 · KROK (Dentistry)
A patient with acute cardiac failure has been taking cardiac glycoside drug for a long time. He has developed the following symptoms: nausea, fatigue, extrasystole. What is the cause of these symptoms?
- A. Functional cumulation
- B. Acquired tolerance
- C. Material cumulation
- D. Idiosyncrasy
- E. Drug addiction
Hint
Recall what happens to a highly protein-bound drug with a very long half-life when it is taken repeatedly over a long period.
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