KROK 1 Stomatology 2015 – Question 147 · KROK (Dentistry)
Pyrogenal administered to a rabbit, in the course of an experiment, resulted in increase of its body temperature. What substance of those named below acts as a secondary pyrogen that is a part of fever-inducing mechanism?
- A. Immunoglobulin
- B. Histamine
- C. Bradykinin
- D. Pseudomonas polysaccharide (Piromen)
- E. Interleukin 1
Hint
Distinguish exogenous pyrogens from the endogenous mediators released by leukocytes that act on the hypothalamic thermoregulatory centre.
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