KROK 1 Stomatology 2015 – Question 118 · KROK (Dentistry)
Osteolathyrism is characterized by a decrease in collagen strength caused by much less intensive formation of cross-links in the collagen fibrils. This phenomenon is caused by hypoactivity of the following enzyme:
- A. Lysyl oxidase
- B. Collagenase
- C. Monoamine oxidase
- D. Lysyl hydroxylase
- E. Prolyl hydroxylase
Hint
Think which copper-dependent extracellular enzyme converts lysine residues into aldehydes that form covalent cross-links between tropocollagen molecules.
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