KROK 1 Stomatology 2014 – Question 126 · KROK (Dentistry)
Patients with erythropoietic porphyria (Gunther’s disease) have teeth that fluoresce red on exposure to ultraviolet light; photosensitive skin; red urine. This disease is associated with the lack of the following enzyme:
- A. Uroporphyrinogen decarboxylase
- B. Delta-aminolevulinate synthase
- C. Uroporphyrinogen-I synthase
- D. Ferrochelatase
- E. Uroporphyrinogen-III cosynthase
Hint
Gunther's disease is a congenital erythropoietic porphyria in which type I porphyrins accumulate; think about at which step of haem synthesis the type III isomer is normally formed.
The answer, the explanation and a note on every option are available once you log in. The account is free: topic tests, a mock exam, mistake review and statistics.