KROK 1 Stomatology 2014 – Question 110 · KROK (Dentistry)
A 24-year-old patient with catarrhal tonsillitis has been administered a drug from the group of sulfonamides. Specify the mechanism of sulfonamide antibacterial action:
- A. Disruption of the cell wall protein synthesis
- B. Inhibition of sulfhydryl groups of thiol enzymes
- C. Reduction of membrane permeability
- D. Competitive antagonism of PABA
- E. Protein coagulation
Hint
Recall the structural similarity of sulfonamides to the substrate bacteria use to synthesise folic acid.
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