KROK 1 Stomatology 2014 – Question 80 · KROK (Dentistry)

A 25-year-old patient with a hereditary enzymopathy (Gilbert’s disease) has a disorder of bilirubin conjugation in liver. What enzyme is not synthesized in this patient?

  1. A. UDP-glycogen transferase
  2. B. UDP-glucose pyrophosphorylase
  3. C. Ornithine carbamoyltransferase
  4. D. UDP-glucuronyl transferase
  5. E. Amidophosphoribosyltransferase
Hint

Gilbert's syndrome is a defect of bilirubin conjugation, so think about which conjugating group is added to bilirubin in the hepatocyte and which enzyme family transfers it.

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