KROK 1 Stomatology 2014 – Question 45 · KROK (Dentistry)
A 10-year-old child cut his leg with a piece of glass and was sent to a clinic for an anti-tetanus serum injection. In order to prevent the development of anaphylactic shock, the Besredka desensitization method was applied. What mechanism underlies this method?
- A. Binding to IgE fixed to mast cells
- B. Binding of IgE receptors on mast cells
- C. Stimulation of the immunological antigen tolerance
- D. Inhibited synthesis of mast cells mediators
- E. Stimulation of antigen-specific IgG2 synthesis
Hint
Recall that this method administers the serum in small fractional doses first and think about what those small antigen doses do to sensitised mast cells.
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