KROK 1 Stomatology 2013 – Question 108 · KROK (Dentistry)

Survey radiograph of facial skull of a 16-year-old girl shows some hole-like foci of cranial bone destruction. Histological examination of biopsy material revealed zones of destruction of bone trabeculae, proliferation of connective tissue with diffuse histiocytic infiltrate and a large number of eosinophilic leukocytes. Diagnose the disease:

  1. A. Eosinophilic granuloma
  2. B. Fibrous dysplasia
  3. C. Cherubism
  4. D. Osteoclastoma
  5. E. Histiocytosis X
Hint

Focus on the combination of punched-out skull lesions in a young patient with histiocytic proliferation rich in eosinophils.

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