KROK 1 Stomatology 2013 – Question 64 · KROK (Dentistry)
A patient with acute heart failure refractory to cardiac glycosides was given an injection of dobutamine. What is the mechanism of action of this drug?
- A. Complexation with membrane phospholipids
- B. Inhibition of phosphodiesterase activity
- C. Inhibition of K⁺, Na⁺-ATPase
- D. Stimulation of β-1-adrenergic receptors
- E. Increase of n. vagus tonus
Hint
Think of dobutamine as a synthetic catecholamine and which receptor type in the myocardium it selectively activates to raise contractility.
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