KROK 1 Stomatology 2013 – Question 54 · KROK (Dentistry)
Having recovered from angina a 23-year-old patient developed urinary syndrome (hematuria, proteinuria, leukocyturia). Study of the puncture biopsy of a kidney revealed manifestations of intracapillary proliferative glomerulonephritis, and electron microscopy revealed large subepithelial deposits. What is the pathogenesis of this disease?
- A. Atopy, anaphylaxis with production of IgE and their fixation to the mast cells
- B. Immunocomplex mechanism
- C. Granulomatosis
- D. Cytotoxic, cytolytic action of antibodies
- E. Cell-mediated cytolysis
Hint
Consider what the large subepithelial electron-dense 'humps' found after a streptococcal throat infection are made of and which hypersensitivity type they represent.
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