KROK 1 Stomatology 2013 – Question 44 · KROK (Dentistry)

A 10-year-old child cut his leg with a piece of glass and was sent to a clinic for an anti-tetanus serum injection. In order to prevent the development of anaphylactic shock the Besredka desensitisation method was applied. What mechanism underlies this method?

  1. A. Binding to IgE fixed to mast cells
  2. B. Stimulation of the immunological antigen tolerance
  3. C. Inhibited synthesis of mast cells mediators
  4. D. Stimulation of antigen-specific IgG2 synthesis
  5. E. Binding of IgE receptors on mast cells
Hint

Think about what happens when small fractional doses of the allergen meet antibodies already sitting on sensitized cells.

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