KROK 1 Stomatology 2013 – Question 32 · KROK (Dentistry)

Certain infections caused by bacteria are treated with sulphanilamides that block the synthesis of bacterial growth factor. What is the mechanism of these drugs action?

  1. A. They inhibit the folic acid absorption
  2. B. They are allosteric enzyme inhibitors
  3. C. They are antivitamins of para-aminobenzoic acid
  4. D. They are allosteric enzymes
  5. E. They are involved in redox processes
Hint

Consider the structural similarity between sulphanilamides and the substrate bacteria use to build their own folate.

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