KROK 1 Stomatology 2012 – Question 167 · KROK (Dentistry)
Skin of patients with pigment xeroderma is very sensitive to the sun radiation, there is a risk of skin cancer development. The reason for this is hereditary deficiency of UV-endonuclease. As a result of this defect the following process is disturbed:
- A. DNA reparation
- B. DNA replication
- C. Transcription
- D. Initiation
- E. Translation
Hint
UV light creates pyrimidine dimers in DNA. Ask which process normally cuts them out.
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