KROK 1 Stomatology 2012 – Question 138 · KROK (Dentistry)

Osteolathyrism is characterized by a decrease in collagen strength caused by much less intensive formation of crosslinks in collagen fibrils. This phenomenon is caused by the low activity of the following enzyme:

  1. A. Lysyl oxidase
  2. B. Collagenase
  3. C. Lysyl hydroxylase
  4. D. Monoamine oxidase
  5. E. Prolyl hydroxylase
Hint

Think about the copper-dependent extracellular enzyme that converts lysine residues into reactive aldehydes, and which is inhibited by lathyrogens.

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